Argireline

Argireline, or acetyl hexapeptide-3, ia a unique peptide that reduces the degree of existing facial wrinkles and inhibits the develpment of new ones by modulating facial muscle contraction.  In short, it addresses the lines and wrinkles caused by repeated facial expressions.  It targets the same wrinkle formation as Botulinim toxin but in a very different way. 

When the nerves in the face are stimulated, they release a chemical messenger, called a neurotransmitter, that instructs the muscle to contract.  The neurotransmitters are contained in vesicles at the end of the nerve cell.  In order for the neurotransmitter to be released to the muscle, a protein on the vesicle,(VAMP), must link to a protein on the nerve membrane (Syntaxin).  This can only be accomplished with the aid of a connector protein (SNAP-25).  Once these proteins have linked together to form what is called a SNARE complex, the nerve cell is able to discharge the chemical messenger and cause the muscle response. 

Argireline works by competing for position with the SNAP-25 connector protein.  When it is present in the SNARE complex rather than SNAP-25, the complex is slightly destabilized and the vesicles can not release the neurotransmitters efficiently.  As a result muscle contraction is weakened, preventing the formation of lines and wrinkles.

Argireline is effective at reducing the depth of wrinkles on the face that are the result of repeated contraction of the muscles of facial expression, particularly in the forehead and around the eyes.  It is a safer, cheaper, and milder alternative to invasive Botulinim toxin injections.  A list of skin care products that incorporate Argireline as an ingredient are:

Peter Thomas Roth Ultra Lite Anti-Aging Cellular Repair

Peter Thomas Roth Ultra Lite Anti-Aging Cellular Repair

Give your skin intense wrinkle repair without the feeling of a heavy mask on your face. Peter Thomas Roth Ultra-Lite Anti-Aging Cellular Repair TM targets the muscle groups that cause facial wrinkles and helps to boost collagen and elastin in the skin.


HydroPeptide Face - Intensive Concentrate Anti-Aging Corrective Creme

HydroPeptide Face - Intensive Concentrate Anti-Aging Corrective Creme

HydroPeptide is a breakthrough formulation that maximizes penetration with six clinically-proven peptides and over ten state-of-the-art antioxidants that visibly lift away the look of fine lines to reveal smoother, more elastic, glowing skin. 93% of subjects displayed a measurable reduction in the appearance of sagging skin, fine lines and wrinkles. HydroPeptide combines therapy and luxury; a silky emulsion of blissful elegance united into one convenient, results-driven cream.